inglés al español Medicina Medicina: Farmacia

En un estudio titulado: "Calcium Supplementation and the Risks of Atherosclerotic Vascular Disease in Older Women: Results of a 5-Year RCT and a 4.5-Year Follow-up":

"Fourteen hundred and sixty women were recruited from the electoral role for the Calcium Intake Fracture Outcome Study (CAIFOS), a 5-year population-based study of ambulatory Western Australian women aged over 70 years designed to investigate the efficacy of calcium supplementation in preventing fracture. A recruitment letter was sent to 24,800 potentially eligible women using the electoral roll. Because voting is compulsory for adult Australians, nearly 100% of women of this age are registered. Potential participants were excluded if they had an illness likely to limit involvement in the study for 5 years or they were taking **bone-active agents** such as bisphosphonates or estrogen. "

¿Cómo se traduce "bone-active agents"? No lo encuentro en ninguno de mis diccionarios o glosarios. Lo único que se me ocurre es medicamentos o fármacos para los huesos y me imagino que existe una manera más específica y puntual de traducirlo.

Mil gracias por adelantado.