Oct 27, 2021 00:54
3 yrs ago
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inglés term

inflammasome

GBK inglés al español Medicina Medicina (general)
Definition from Oxford English Dictionary:
A complex of proteins in the cytoplasm that regulates the activation of enzymes involved in immune and inflammatory responses to pathogens.
Example sentences:
Appropriate inflammasome activation is vital for the host to cope with foreign pathogens or tissue damage, while aberrant inflammasome activation can cause uncontrolled tissue responses that may contribute to various diseases, including autoinflammatory disorders, cardiometabolic diseases, cancer and neurodegenerative diseases. (Nature Portfolio)
The adaptor protein ASC must become linearly ubiquitinated and phosphorylated for inflammasome assembly to occur. After priming, canonical NLRP3 inflammasome activation requires a second, distinct signal to activate NLRP3 and lead to the formation of the NLRP3 inflammasome complex. (National Center for Biotechnology Info)
Potassium ion efflux (a common inflammasome activator) is an essential factor for the assembly and up-regulation of NLRP3 complexes induced by the agonist adenosine triphosphate (ATP). (Molecular Cancer)
Proposed translations (español)
4 +2 inflamasoma
Change log

Oct 22, 2021 11:51: changed "Kudoz queue" from "In queue" to "Public"

Oct 27, 2021 00:55: changed "Stage" from "Preparation" to "Submission"

Oct 30, 2021 01:56: changed "Stage" from "Submission" to "Selection"

Nov 6, 2021 01:54:

Nov 6, 2021 19:54: changed "Stage" from "Selection" to "Completion"

Discussion

Hernan Casasbuenas Oct 30, 2021:
Para dar fuerza a la respuesta https://idus.us.es/bitstream/handle/11441/50469/Pérez Márque...
Esta publicación universitaria da fuerza a la traducción propuesta.

Proposed translations

+2
8 horas
Selected

inflamasoma

Definition from Saval Net:
El inflamasoma es una estructura conformada por proteínas intracelulares implicadas en el inicio de la respuesta inflamatoria por estímulo intracelular.
Example sentences:
Un inflamasoma representa un complejo de alto peso molecular que activa las caspasas inflamatorias y activa las citocinas de la familia IL-1. (Labclinics)
Inflamasoma y sistema inmune: Importancia sobre la salud del hígado. (G-SE)
Peer comment(s):

agree Hernan Casasbuenas : The term is clearly stated in multiple Medical publications: https://revistas.unal.edu.co › ...PDFRol del inflamasoma en la génesis del cáncer de cabeza y cuello
12 horas
Gracias, Hernan.
agree Michael Chirichigno : inflamasoma
10 días
Gracias, Michael.
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