Sep 18, 2006 16:49
17 yrs ago
1 viewer *
German term

in geringem Ausmaß

German to English Medical Medical: Pharmaceuticals
Bisoprolol kann durch Hemmung von ß2-Rezeptoren in geringem Ausmaß eine Erhöhung des Tonus der glatten Muskulatur bewirken.

(Does it mean "slight inhibition" or "a slight increase"?)
Change log

Sep 18, 2006 19:46: Steffen Walter changed "Field (specific)" from "Medical (general)" to "Medical: Pharmaceuticals"

Discussion

archtrans Sep 18, 2006:
I originally thought it did not specify the magnitude of the increase of the muscle tone, only the extent of the Hemmung, but re-reading it, I suspect it does indicate a slight increase of muscle tone. I would defer to a native German speaker, however!
njbeckett (asker) Sep 18, 2006:
But my question is: Is it a slight inhibition of the beta 2 receptors or a slight increase in the tonus of the smooth musculature? Or does it mean both?

Proposed translations

+3
7 hrs
Selected

. . . can effect a minor increase in . . .

Pons, Romain, Dietl/Lorenz
Peer comment(s):

agree Martina Keskintepe : nicely put Karin
5 hrs
agree Anne Schulz : "...via inhibition of ß2 receptors." IMO the original is ambiguous on purpose. Bisoprolol is a ß1-"selective" blocker, so it says there is only minor effect on ß2 receptors resulting in a slight effect on smooth muscle tone.
7 hrs
agree Dr. Georg Schweigart
8 hrs
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4 KudoZ points awarded for this answer. Comment: "I think you are right. The original is intentionally ambiguous and refers to both the effect on the receptors and the tonus."
+1
2 mins

in small quantities.

effects of taking b. can have positive effects taken in small doses.
Peer comment(s):

agree Fabio Descalzi
3 mins
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14 mins

to a slight extent

Not totally sure, but I think the phrase refers to the effect, not the quantity or dose. The Hemmung effect on the receptors is minimal, which is enough to increase muscle tone.
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+2
17 mins

it has a limited effect on....

-

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Note added at 25 mins (2006-09-18 17:15:15 GMT)
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...the increase of smooth muscle tone. :-)
Peer comment(s):

agree Martina Keskintepe : definitely! Otherwise the sentence structure would be different and would i.e. say "geringe Hemmung von".
44 mins
agree Dr. Georg Schweigart
15 hrs
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17 mins

to a small/moderate extent (perhaps?)

.

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Note added at 35 mins (2006-09-18 17:24:27 GMT)
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As far as I am concerned the increase pertains to the receptors
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