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English to Portuguese - Rates: 0.05 - 0.05 USD per word / 20 - 30 USD per hour English - Rates: 0.05 - 0.05 USD per word / 20 - 30 USD per hour Portuguese to English - Rates: 0.05 - 0.05 USD per word / 20 - 30 USD per hour Spanish to English - Rates: 0.05 - 0.05 USD per word / 20 - 30 USD per hour English to Spanish - Rates: 0.05 - 0.05 USD per word / 20 - 30 USD per hour
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English to Portuguese: Demineralised human dentine matrix stimulates theexpression of VEGF and accelerates the bone repair in tooth sockets of rats General field: Medical Detailed field: Medical: Dentistry
Source text - English A b s t r a c t
Objective: In this study we investigated the possible use of human demineralised dentine matrix (DHDM), obtained from the extracted teeth, as bone graft material and evaluated the expression of vascular endothelial growth factor (VEGF) induced by this material in the healing process of tooth sockets of rats.
Design: To evaluate bone regeneration and expression of VEGF induced by DHDM, thirty-two male Wistar rats weighing approximately 200 g were used. After maxillary second molar
extraction, the left sockets were filled with DHDM and the right sockets were naturally filled by blood clot (control). The animals were sacrificed at 3, 7, 14 and 21 days after surgery and upper maxillaries were processed for histological, morphometric and immunohistochemi-cal analyses. DHDM was used to evaluate the mechanical effect of bone graft material into sockets. Expression of VEGF was determined by immunohistochemistry in all groups.
Results: Our results demonstrated a significant increase in the newly formed bone tissue in sockets of 7, 14 and 21 days and a significant increase in VEGF expression at days 7 and 14 on treated sockets.
Conclusions: Our results showed that DHDM increases the expression of VEGF and accelerates the healing process in rats tooth sockets, by stimulating bone deposition and also vessels formation. These results suggest that DHDM has osteoinductive/osteoconductive potential and may represent an efficient grafting material on guided bone regeneration.
1. Introduction
Despite the high potential for regeneration of bone tissue, some repairs may be accompanied by intrabony defects so that and the repair of complex fractures and large bone defects, caused by several aetiological factors such as trauma, diseases, development deformities or tumour resection, often becomes frustrating.
One of the goals of skeletal tissue therapies is to accelerate the healing process, decreasing the period of bone maturation. Many strategies have been developed and tested to improve and accelerate bone repair, including the use of bone grafts and growth factors.2,3 However, classic bone grafting techniques, when used, rarely provide satisfactory results,4–6 and the use of growth factors may be infeasible because of the expensive costs.
Translation - Portuguese Matriz desmineralizada da dentina humana estimula a expressão de VEGF e acelera a reparação óssea em alvéolos de dentes de ratos
Resumo
Objetivo: Neste estudo nós investigamos a possibilidade da utilização da matriz de dentina humana desmineralizada (DHDM), obtida a partir de dentes extraídos, usados como enxerto ósseo e avaliamos a expressão do fator de crescimento endotelial vascular (VEGF), que foi induzida por este material no processo de cicatrização de alvéolos dentários de ratos.
Método: Para avaliar a regeneração óssea e a expressão do VEGF induzida pelo DHDM, foram utilizados 32 ratos machos da raça Wistar, pesando aproximadamente 200 g. Após a extração do segundo molar superior, os alvéolos da esquerda foram preenchidos com DHDM e as alvéolos da direita foram naturalmente preenchidos com coágulo de sangue (de controle). Os animais foram sacrificados aos 3, 7, 14 e 21 dias após a cirurgia e os maxilares superiores foram processados para análise histológica, morfométrica e imunohistoquímica. O DHDM foi utilizado para avaliar o efeito mecânico do enxerto ósseo nos alvéolos. A expressão de VEGF foi determinada por imunohistoquímica em todos os grupos.
Resultados: Os resultados demonstraram um aumento significativo no tecido ósseo recém-formado nos alvéolos após 7, 14 e 21 dias e um aumento significativo na expressão de VEGF após 7 e 14 dias nos alvéolos tratados.
Conclusões: Nossos resultados mostraram que o DHDM aumenta a expressão de VEGF e acelera o processo de cicatrização em alvéolos dentários de ratos, ao estimular a deposição óssea e também a formação de vasos. Estes resultados sugerem que o DHDM possui um potencial osteoindutor/osteocondutor e pode ser eficiente na regeneração óssea assistida.
1. Introdução
Apesar do elevado potencial regenerativo do tecido ósseo, os processos de reparação podem causar alguns defeitos intraósseos. Desta forma, a reparação de fraturas complexas e defeitos ósseos maiores, causados por diversos fatores etiológicos como trauma, doenças, deformidades de desenvolvimento ou ressecção do tumor, muitas vezes é frustrada.
Um dos objetivos dos tratamentos de tecidos esqueléticos é acelerar o processo de cura, reduzindo o período de maturação óssea. Muitas estratégias têm sido desenvolvidas e testadas para melhorar e acelerar a reparação óssea, incluindo o uso de enxertos ósseos e fatores de crescimento. No entanto, as técnicas clássicas de enxerto ósseo, quando utilizadas, raramente fornecem resultados satisfatórios, e o uso de fatores de crescimento pode ser inviável devido aos custos elevados.
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Translation education
Master's degree - Cambridge University
Experience
Years of experience: 21. Registered at ProZ.com: Feb 2013.
English (Universidade Federal de Uberlândia, verified) English to Portuguese (Universidade Federal de Uberlândia) English (Universidade Federal de Uberlândia) English (Universidade Federal de Uberlândia) Portuguese to English (Cambridge University (ESOL Examinations))
Memberships
N/A
Software
Adobe Acrobat, Adobe Illustrator, Adobe Photoshop, AutoCAD, Catalyst, Fluency, Indesign, Microsoft Excel, Microsoft Office Pro, Microsoft Word, memoQ, SDL Trados, Swordfish, Trados Studio, TransSuite2000
CV/Resume
CV available upon request
Professional objectives
Meet new translation company clients
Get help on technical issues / improve my technical skills
Meet new end/direct clients
Work for non-profits or pro-bono clients
Screen new clients (risk management)
Network with other language professionals
Find trusted individuals to outsource work to
Build or grow a translation team
Get help with terminology and resources
Learn more about translation / improve my skills
Help or teach others with what I have learned over the years
Transition from freelancer to agency owner
Bio
I am an English – Portuguese - Spanish translator based in
Brazil and I would like to offer my services to your agency/ company.
My specializations include: Mobile Game LQA,Transcriptions, Mobile App
translations, Localization, Telecommunications, Medical, expert fashion, Psychology,
Law, Industrial, Engineering, Technical and Business translations, due to
experience in a worldwide company and as a freelancer working in many different
projects.
I can work with files created with all main MS Office programs such as
Word, PowerPoint and Publisher and complex PDF or InDesign files can be
processed with an external partner, always observing confidentiality.
With each freelance project I undertake, I guarantee high quality work
delivered on deadline.
I am a fast learner and can incorporate myself fairly well in various
working environments. I am sure I will be a good addition to your team and will
greatly contribute to its productivity.
Keywords: portuguese, english, Human Resources, healthcare, medical, financial, computers, translations, localization, technology. See more.portuguese, english, Human Resources, healthcare, medical, financial, computers, translations, localization, technology, marketing, jornalism, management, transportation, history, bible, editing, revision, . See less.
Expertise