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Source text - English 1. Introduction
Most cancer patients will experience anaemia at some point in their treatment, either as a result of their underlying malignancy or because of the treatment received.1 Anaemia has a major impact on nearly all of the organ systems of the body and results in a variety of symptoms, particularly fatigue, that have a detrimental effect upon the patient’s Quality of Life (QoL).2 In addition, numerous studies have shown that the presence of anaemia is an adverse prognostic factor in patients with cancer and is associated with reduced survival.3,4
Historically, anaemia was treated with blood transfusions. However, blood is a scarce and increasingly expensive product and blood transfusions offer only transitory benefits. In addition, blood transfusions are associated with appreciable risks to the patient and they are now largely reserved as an emergency measure for patients with severe anaemia who require rapid correction of very low haemoglobin (Hb) levels (reviewed in Chapter 3).
Translation - Spanish 1. Introducción
La mayoría de los pacientes con cáncer experimentan anemia en algún momento de su tratamiento, ya sea como resultado de la neoplasia subyacente o por el tratamiento recibido.1 La anemia tiene un impacto grave en casi todos los órganos y sistemas del cuerpo, y resultan una variedad de síntomas, particularmente fatiga, que tiene un efecto perjudicial sobre la calidad de vida del paciente (QoL). 2 Además, numerosos estudios han demostrado que la presencia de la anemia es un factor adverso de pronóstico en los pacientes con cáncer y está asociada con la reducción de la sobrevida. 3,4
Históricamente, la anemia era tratada con transfusiones de sangre. Sin embargo, la sangre es escasa y cada vez un producto más costoso, y las transfusiones de sangre ofrecen solamente beneficios transitorios. Además, las transfusiones de sangre se asocian con riesgos apreciables para el paciente y ahora se reservan en gran parte como medida de emergencia para los pacientes con anemia grave que requieren una corrección rápida de los niveles muy bajos de hemoglobina (Hb) (estudiado en el capítulo 3).
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Years of experience: 24. Registered at ProZ.com: Aug 2004.
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