solución inyectable para infusión

English translation: solution for infusion / solution for intravenous use

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
Spanish term or phrase: solución inyectable para infusión
English translation:solution for infusion / solution for intravenous use
Entered by: sebaspedlp

19:08 Feb 22, 2016
Spanish to English translations [PRO]
Medical - Medical: Pharmaceuticals / trabajo práctico faculta
Spanish term or phrase: solución inyectable para infusión
Composición: Cada frasco-ampolla con 50 ml de solución inyectable para infusión contiene: 10 mg de Nimodipino. Este medicamento contiene 1 mmol (frasco de 50 ml) de sodio por dosis. Esto debe tenerse en cuenta en pacientes con dieta controlada de sodio. Excipientes: Etanol, Polietilenglicol, Citrato Sódico Dihidratado, Acido Cítrico, Agua para Inyectables.
Descripción: Forma farmacéutica: Solución para infusión intravenosa.
Accion Terapeutica: Codigo ATC: C08 CA06.
Indicaciones: Profilaxis y tratamiento de los deficit neurologicos isquemicos secundarios a vasospasmo cerebral despues de una hemorragia subaracnoidea de origen aneurismitico.

injectable solution for administration???????
sebaspedlp
Argentina
Local time: 03:30
solution for infusion / solution for intravenous use
Explanation:
"injectable" is unnecessary, you won't inject an infusion solution, but infuse it!

"solution for intravenous use" is the EMA preferred term for IV solutions. However, I guess your translation is for the US?


"1. Name of the medicinal product

Nimotop 0.02% Solution for Infusion.

2. Qualitative and quantitative composition

A sterile solution containing 10 mg nimodipine in 50 ml vials of aqueous alcoholic solvent (0.02%).

3. Pharmaceutical form

Clear yellow sterile solution for intravenous use.

4. Clinical particulars
4.1 Therapeutic indications

Nimodipine is indicated for the treatment of ischaemic neurological deficits following aneurysmal subarachnoid haemorrhage.

4.2 Posology and method of administration

Recommended dose - Aneurysmal Subarachnoid Haemorrhage

For the first two hours of treatment 1 mg of nimodipine, i.e. 5 ml Nimotop solution, (about 15 μg/kg bw/h), should be infused each hour via a central catheter. If it is well tolerated, the dose should be increased after two hours to 2 mg nimodipine, i.e. 10 ml Nimotop solution per hour (about 30 μg/kg bw/h), providing no severe decrease in blood pressure is observed.

Patients of body weight less than 70 kg or with unstable blood pressure should be started on a dose of 0.5 mg nimodipine per hour (2.5 ml of Nimotop solution), or less if necessary."

https://www.medicines.org.uk/emc/medicine/5581


This second ref is from New Zealand and uses "intravenous infusion solution"

http://www.medsafe.govt.nz/profs/datasheet/n/nimotoptabinf.p...



The problems mentioned by Helena are concerned with the IV administration of Nimodipine ORAL CAPSULES - which are not for IV admin, but apparently have been opened and the liquid inside administered IVly.
http://www.drugs.com/pro/nimotop.html
Selected response from:

Neil Ashby
Spain
Local time: 08:30
Grading comment
thank you so much
4 KudoZ points were awarded for this answer



Summary of answers provided
5 +2solution for infusion / solution for intravenous use
Neil Ashby
5 +1injectable solution for infusion
Jesus Duran Fernandez
3intravenous infusion
lugoben
Summary of reference entries provided
Information about Nimodipine
Helena Chavarria

  

Answers


14 mins   confidence: Answerer confidence 3/5Answerer confidence 3/5
intravenous infusion


Explanation:
Intravenous infusion, administering a drug or other substance as part of a liquid solution injected directly into a vein (usually in the arm) at a prescribed rate.
http://forum.wordreference.com/threads/infusión.142131/

--------------------------------------------------
Note added at 19 mins (2016-02-22 19:27:03 GMT)
--------------------------------------------------

Intravenous therapy (IV therapy or iv therapy in short) is the infusion of liquid substances directly into a vein. Intravenous simply means "within vein". Therapies administered intravenously are often included in the designation of specialty drugs. Intravenous infusions are commonly referred to as drips because many systems of administration employ a drip chamber, which prevents air from entering the blood stream (air embolism), and allows an estimation of flow rate.
https://en.wikipedia.org/wiki/Intravenous_therapy

Por loc ual, también se suele llamar : infusion therapy


lugoben
Local time: 02:30
Native speaker of: Spanish
PRO pts in category: 14
Notes to answerer
Asker: muchas gracias

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22 mins   confidence: Answerer confidence 5/5 peer agreement (net): +1
injectable solution for infusion


Explanation:
Infusión es infusion en ingles


    Reference: http://www.linguee.es
Jesus Duran Fernandez
Spain
Local time: 08:30
Works in field
Native speaker of: Spanish
Notes to answerer
Asker: muchas gracias


Peer comments on this answer (and responses from the answerer)
agree  cristina orriols
5 mins
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12 hrs   confidence: Answerer confidence 5/5 peer agreement (net): +2
solution for infusion / solution for intravenous use


Explanation:
"injectable" is unnecessary, you won't inject an infusion solution, but infuse it!

"solution for intravenous use" is the EMA preferred term for IV solutions. However, I guess your translation is for the US?


"1. Name of the medicinal product

Nimotop 0.02% Solution for Infusion.

2. Qualitative and quantitative composition

A sterile solution containing 10 mg nimodipine in 50 ml vials of aqueous alcoholic solvent (0.02%).

3. Pharmaceutical form

Clear yellow sterile solution for intravenous use.

4. Clinical particulars
4.1 Therapeutic indications

Nimodipine is indicated for the treatment of ischaemic neurological deficits following aneurysmal subarachnoid haemorrhage.

4.2 Posology and method of administration

Recommended dose - Aneurysmal Subarachnoid Haemorrhage

For the first two hours of treatment 1 mg of nimodipine, i.e. 5 ml Nimotop solution, (about 15 μg/kg bw/h), should be infused each hour via a central catheter. If it is well tolerated, the dose should be increased after two hours to 2 mg nimodipine, i.e. 10 ml Nimotop solution per hour (about 30 μg/kg bw/h), providing no severe decrease in blood pressure is observed.

Patients of body weight less than 70 kg or with unstable blood pressure should be started on a dose of 0.5 mg nimodipine per hour (2.5 ml of Nimotop solution), or less if necessary."

https://www.medicines.org.uk/emc/medicine/5581


This second ref is from New Zealand and uses "intravenous infusion solution"

http://www.medsafe.govt.nz/profs/datasheet/n/nimotoptabinf.p...



The problems mentioned by Helena are concerned with the IV administration of Nimodipine ORAL CAPSULES - which are not for IV admin, but apparently have been opened and the liquid inside administered IVly.
http://www.drugs.com/pro/nimotop.html

Neil Ashby
Spain
Local time: 08:30
Specializes in field
Native speaker of: English
PRO pts in category: 136
Grading comment
thank you so much

Peer comments on this answer (and responses from the answerer)
agree  Helena Chavarria
57 mins
  -> Thanks Helena, I guessed you posted the ref when tired or something...

agree  neilmac
1 day 37 mins
  -> Cheers Mac
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Reference comments


21 mins peer agreement (net): +1
Reference: Information about Nimodipine

Reference information:
If the patient is unable to take tablets orally, it was previously given via intravenous infusion at a rate of 1–2 mg/hour (lower dosage if the body weight is <70 kg or blood pressure is too low),[1] but since the withdrawal of the IV preparation, administration by nasogastric tube is an alternative.

https://en.wikipedia.org/wiki/Nimodipine

Nimotop 0.02% Solution for Infusion.
2. Qualitative and quantitative composition
A sterile solution containing 10 mg nimodipine in 50 ml vials of aqueous alcoholic solvent (0.02%).

https://www.medicines.org.uk/emc/medicine/5581

Nimodipine should not be administered IV or by other parenteral routes. Deaths and serious life threatening adverse events have been reported when the contents of nimodipine capsules were injected parenterally. Healthcare providers who prescribe, dispense, or administer nimodipine should be instructed to administer nimodipine capsules orally only. If nimodipine is inadvertently administered IV, clinically significant hypotension may require cardiovascular support with pressor agents. Specific treatments for calcium channel blocker overdose should also be given promptly.

http://www.drugs.com/dosage/nimodipine.html

I was going to suggest 'solution for intravenous infusion' but I've read that the drug must not be administered intravenously.


--------------------------------------------------
Note added at 26 mins (2016-02-22 19:34:18 GMT)
--------------------------------------------------

The drug is also called Nimotop

NIMOTOP CONCENTRATED INTRAVENOUS INFUSION SOLUTION
Each bottle of 50 mL Nimotop concentrated intravenous infusion solution contains 10mg nimodipine in 50 mL alcoholic solvent.

http://www.medsafe.govt.nz/profs/datasheet/n/nimotoptabinf.p...

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Note added at 1 day2 hrs (2016-02-23 21:34:16 GMT) Post-grading
--------------------------------------------------

Glad to be of help :-)

Helena Chavarria
Spain
Native speaker of: Native in EnglishEnglish
PRO pts in category: 84
Note to reference poster
Asker: thank you for your time posting this!


Peer comments on this reference comment (and responses from the reference poster)
agree  Neil Ashby: The problems relate to infusing the liquid extracted from Nimodipone oral capsules (suprising that healthcare professionals would do that, but apparently they do). // No worries Helena, can't be knocked for trying to help ;@)
12 hrs
  -> I was tired when I posted these references and I didn't read them properly. But knowing the question comes from a university assignment, alarm bells started ringing in my head! I thought maybe the teachers were trying to catch students out.
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