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19:08 Feb 22, 2016 |
Spanish to English translations [PRO] Medical - Medical: Pharmaceuticals / trabajo práctico faculta | |||||||
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| Selected response from: Neil Ashby Spain Local time: 08:30 | ||||||
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5 +2 | solution for infusion / solution for intravenous use |
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5 +1 | injectable solution for infusion |
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3 | intravenous infusion |
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Information about Nimodipine |
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intravenous infusion Explanation: Intravenous infusion, administering a drug or other substance as part of a liquid solution injected directly into a vein (usually in the arm) at a prescribed rate. http://forum.wordreference.com/threads/infusión.142131/ -------------------------------------------------- Note added at 19 mins (2016-02-22 19:27:03 GMT) -------------------------------------------------- Intravenous therapy (IV therapy or iv therapy in short) is the infusion of liquid substances directly into a vein. Intravenous simply means "within vein". Therapies administered intravenously are often included in the designation of specialty drugs. Intravenous infusions are commonly referred to as drips because many systems of administration employ a drip chamber, which prevents air from entering the blood stream (air embolism), and allows an estimation of flow rate. https://en.wikipedia.org/wiki/Intravenous_therapy Por loc ual, también se suele llamar : infusion therapy |
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injectable solution for infusion Explanation: Infusión es infusion en ingles Reference: http://www.linguee.es |
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solution for infusion / solution for intravenous use Explanation: "injectable" is unnecessary, you won't inject an infusion solution, but infuse it! "solution for intravenous use" is the EMA preferred term for IV solutions. However, I guess your translation is for the US? "1. Name of the medicinal product Nimotop 0.02% Solution for Infusion. 2. Qualitative and quantitative composition A sterile solution containing 10 mg nimodipine in 50 ml vials of aqueous alcoholic solvent (0.02%). 3. Pharmaceutical form Clear yellow sterile solution for intravenous use. 4. Clinical particulars 4.1 Therapeutic indications Nimodipine is indicated for the treatment of ischaemic neurological deficits following aneurysmal subarachnoid haemorrhage. 4.2 Posology and method of administration Recommended dose - Aneurysmal Subarachnoid Haemorrhage For the first two hours of treatment 1 mg of nimodipine, i.e. 5 ml Nimotop solution, (about 15 μg/kg bw/h), should be infused each hour via a central catheter. If it is well tolerated, the dose should be increased after two hours to 2 mg nimodipine, i.e. 10 ml Nimotop solution per hour (about 30 μg/kg bw/h), providing no severe decrease in blood pressure is observed. Patients of body weight less than 70 kg or with unstable blood pressure should be started on a dose of 0.5 mg nimodipine per hour (2.5 ml of Nimotop solution), or less if necessary." https://www.medicines.org.uk/emc/medicine/5581 This second ref is from New Zealand and uses "intravenous infusion solution" http://www.medsafe.govt.nz/profs/datasheet/n/nimotoptabinf.p... The problems mentioned by Helena are concerned with the IV administration of Nimodipine ORAL CAPSULES - which are not for IV admin, but apparently have been opened and the liquid inside administered IVly. http://www.drugs.com/pro/nimotop.html |
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21 mins peer agreement (net): +1 |
Reference: Information about Nimodipine Reference information: If the patient is unable to take tablets orally, it was previously given via intravenous infusion at a rate of 1–2 mg/hour (lower dosage if the body weight is <70 kg or blood pressure is too low),[1] but since the withdrawal of the IV preparation, administration by nasogastric tube is an alternative. https://en.wikipedia.org/wiki/Nimodipine Nimotop 0.02% Solution for Infusion. 2. Qualitative and quantitative composition A sterile solution containing 10 mg nimodipine in 50 ml vials of aqueous alcoholic solvent (0.02%). https://www.medicines.org.uk/emc/medicine/5581 Nimodipine should not be administered IV or by other parenteral routes. Deaths and serious life threatening adverse events have been reported when the contents of nimodipine capsules were injected parenterally. Healthcare providers who prescribe, dispense, or administer nimodipine should be instructed to administer nimodipine capsules orally only. If nimodipine is inadvertently administered IV, clinically significant hypotension may require cardiovascular support with pressor agents. Specific treatments for calcium channel blocker overdose should also be given promptly. http://www.drugs.com/dosage/nimodipine.html I was going to suggest 'solution for intravenous infusion' but I've read that the drug must not be administered intravenously. -------------------------------------------------- Note added at 26 mins (2016-02-22 19:34:18 GMT) -------------------------------------------------- The drug is also called Nimotop NIMOTOP CONCENTRATED INTRAVENOUS INFUSION SOLUTION Each bottle of 50 mL Nimotop concentrated intravenous infusion solution contains 10mg nimodipine in 50 mL alcoholic solvent. http://www.medsafe.govt.nz/profs/datasheet/n/nimotoptabinf.p... -------------------------------------------------- Note added at 1 day2 hrs (2016-02-23 21:34:16 GMT) Post-grading -------------------------------------------------- Glad to be of help :-) |
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