Reifestörungen [kindlichen]
English translation: maturation disorders [in children]
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| 22:33 Jun 2, 2005 |
| German to English translations [PRO] Medical - Medical: Pharmaceuticals / hormones | |||||||
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|  Selected response from: MMUlr Germany Local time: 20:03 | ||||||
Grading comment
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| Summary of answers provided | ||||
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| 4 +3 | children with growth hormone deficiency (GHD) |
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| 4 +1 | maturation disorders [in children] |
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| 3 +1 | development disturbances (in children) |
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| 4 | developmental disorders |
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Answers
4 mins confidence: 
peer agreement (net): +1
peer agreement (net): +1| Reifestörungen [kindlichen] development disturbances (in children) Explanation: no my area but this might be ok ... not too sure about the "kindlich" here -------------------------------------------------- Note added at 5 mins (2005-06-02 22:39:15 GMT) -------------------------------------------------- or maybe: children with developmental disturbances |
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5 hrs confidence: peer agreement (net): +1
peer agreement (net): +1| Reifestörungen [kindlichen] maturation disorders [in children] Explanation: IMO gonadorelin is the key for this translation issue, and so I tried first to find out, which uses are there for gonadotropin releasing hormone analogs especially in children. See this text: http://www.aetna.com/cpb/data/CPBA0501.html You find that Reifungsstörungen - maturation disorders are sexual or pubertal disorders not meaning "retardation" of the process, but rather precocious puberty which is treated in children - together with infertiliy, also to be found in the table. So I think maturation disorder is the correct term here, and the GH deficiency solution is an interpretation going too far, and maybe into the wrong direction. -------------------------------------------------- Note added at 6 hrs 1 min (2005-06-03 04:34:28 GMT) -------------------------------------------------- Here another text on uses of this drug category - also mentioning delayed puberty (!) -------------------------------------------------- Note added at 6 hrs 1 min (2005-06-03 04:34:43 GMT) -------------------------------------------------- forgot the link: http://www.drugs.com/MMX/Gonadorelin_Acetate.html |
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12 mins confidence: peer agreement (net): +3
peer agreement (net): +3| kindliche Reifestörungen children with growth hormone deficiency (GHD) Explanation: * -------------------------------------------------- Note added at 18 mins (2005-06-02 22:51:32 GMT) -------------------------------------------------- or growth hormone receptor deficiency (GHRD) Gonadorelin ( goe-nad-oh-RELL-in) is a medicine that is the same as gonadotropin-releasing hormone (GnRH) that is naturally released from the hypothalamus gland. http://en.wikipedia.org/wiki/Hypothalamus http://www.becomehealthynow.com/article/bodynervousadvanced/... -------------------------------------------------- Note added at 24 mins (2005-06-02 22:57:59 GMT) -------------------------------------------------- ...The hypothalamus is a substructure of the diencephalon and acts as one of the most significant control centers of the brain. It is located inferior to the thalamus, encapsulates the ventral portion of the third ventricle, and lies just superior to the pituitary gland, which it has direct regulatory control over (Gunderson, 1996). Neurosecretory neurons in the hypothalamus secrete releasing and inhibiting hormones which are carried to the anterior pituitary where they exert their effects via hypothalamic-hypophyseal portal veins. Included in the many functions of the hypothalamus are regulation of food and water intake, autonomic function, emotions, body temperature, motor functions, and circadian sleep-wake cycles (Kalat, 2004). Hormones secreted by the hypothalamus include Thyrotropin- releasing hormone, Gonadotropin-releasing hormone, Growth- releasing hormone... http://www.humboldt.edu/~morgan/hyle_s05.htm -------------------------------------------------- Note added at 35 mins (2005-06-02 23:08:27 GMT) -------------------------------------------------- Growth hormone deficiency (GHD) is a developmental abnormality and it occurs in children who have a deficient pituitary gland that secrets inadequate amount of growth hormone. -------------------------------------------------- Note added at 16 hrs 43 mins (2005-06-03 15:17:17 GMT) -------------------------------------------------- I strongly believe that \'maturation disorder\' would not be the best term to use here, since there are a few very different maturation disorders, and this term is too broad. Gonadorelin is a drug used to cause ovulation in women and for treating growth hormone deficiency in teenagers. I don\'t think it should be implied that this drug may be used for treating any other maturation disorders in children. IMO, I don\'t see why using the terminology \'children with growth hormone deficiency\' would be going too far, if indeed this is exactly part of what this drug is used for. |
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