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bioavailability

Lithuanian translation: Biologinis įsisavinimas

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
English term or phrase:bioavailability
Lithuanian translation:Biologinis įsisavinimas

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16:58 Nov 17, 2009
English to Lithuanian translations [PRO]
Medical - Medical: Pharmaceuticals
Additional field(s): Medical: Cardiology, Medical (general)
English term or phrase: bioavailability
Definition from USC Kidney Transplant Program:
a measure of how much of an administered drug is absorbed into the bloodstream, actually reaching the intended site of action in the body. For example, medicine is absorbed from the GI tract, travels through the bloodstream, and reaches the organ tissues, where it works to fight infection, prevent rejection, etc.

Example sentence(s):
  • Differences in bioavailability among formulations of a given drug can have clinical significance; thus, knowing whether drug formulations are equivalent is essential. Merck & Co., Inc.
  • The term “relative bioavailability” refers to a comparison of two or more dosage forms in terms of their relative rate and extent of absorption. If an intravenous injection is employed as the reference dose, one can determine the absolute bioavailability of the test dosage form. Informa plc
  • Drug candidates can be tested for their desired therapeutic activity, but it is not yet possible to predict whether or not a compound will have sufficient bioavailability to be useful and practical. US National Institutes of Health
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Biologinis įsisavinimas
Definition:
Mano galva, šis terminas tiksliausiai atspindi esmę - tai yra medžiagos dalis, kurią organizmas sugeba įsisavinti.
Selected response from:

Loreta Alechnaviciute Hoffmann
Lithuania
Grading comment
4 KudoZ points were awarded for this answer



Summary of translations provided
5 +2Biologinis įsisavinimas
Loreta Alechnaviciute Hoffmann
4 +1biologinis prieinamumas
Dalia Rokaitė
5Biotinkamumas
Jurga S.


Discussion entries: 1





  

Translations offered


14 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +1
biologinis prieinamumas


Definition from own experience or research:
Skirtingų sudėčių to paties vaisto biologinio prieinamumo skirtumai gali turėti klinikinės reikšmės; taigi svarbiausia žinoti, ar vaisto sudėtis yra vienoda.

Example sentence(s):
  • Kai kuriems geriamiesiems vaistiniams preparatams būdingas mažas biologinis prieinamumas. Tai reiškia, kad, išgėrus vaistinio preparato, jo mažai patenka į sisteminę kraujotaką. - medicine.lt  
Dalia Rokaitė
Lithuania
Local time: 15:02
Native speaker of: Native in LithuanianLithuanian
PRO pts in category: 35

Votes in favor of/against selecting this as the best translation of the term asked
Yes  Rasa Zurbaite: Termino apibrėžimas: http://www.medicine.lt/index.php?pagrid=leidiniai&subid=gm&s... . Dar viena naudinga nuoroda: http://www.kmu.lt/doc/senatas/22-09-02-02-02Biofarmacija_ir_...
4 days
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2 days 21 hrs   confidence: Answerer confidence 5/5
Biotinkamumas


Definition from http://eur-lex.europa.eu:
Vaisto biotinkamumo tyrimas (įvertinimas) atliekamas, kad būtų galima parodyti jo biologinę atitiktį.

Example sentence(s):
  • Piridostigminas, kaip ir kiti šios grupės vaistai, nėra visiškai rezorbuojamas iš virškinimo trakto. Išgerto preparato biotinkamumas yra 3-8 %. Todėl geriamosios vaisto dozės turi būti gerokai didesnės už skiriamas į veną dozes. - www.sveikas.lt  

Explanation:
Be to, sąvoka „bioavailability“ (biotinkamumas) yra įtraukta į LRS terminų glosarijų (žodyną). Žr. http://www3.lrs.lt/pls/term/termp.term_p.
Jurga S.
Lithuania
Local time: 15:02
Native speaker of: Lithuanian
Notes to answerer
Dalia Rokaitė Dėl termino "bioavailability" vertimo: pažiūrėjau Jūsų pateiktą nuorodą (LRS); taip, ten verčiama "biotinkamumas", bet tolesnės nuorodos: Bazė: VDIC Sritis: 5631 žemės ūkio veikla. Bet gi mus domina grynai medicininis kontekstas. Siūlyčiau beatodairiškai nesiremti tokiais glosarijais.

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14 days   confidence: Answerer confidence 5/5 peer agreement (net): +2
Biologinis įsisavinimas


Definition from own experience or research:
Mano galva, šis terminas tiksliausiai atspindi esmę - tai yra medžiagos dalis, kurią organizmas sugeba įsisavinti.

Example sentence(s):
  • www.ktu.lt/lt/mokslas/moksliniai_tyrimai/mt1994/33.pdf 7 psl., antraštė "1994 m. vykdyti moksliniai tyrimai": "Ištirtos mineralinių elementų ir sunkiųjų metalų koncentracijos vaikų mitybos produktuose ir augalinės žaliavos įtaka joms; nustatytos jų biologinio įsisavinimo pradinėse virškinimo sąlygose galimybės " - www.ktu.lt/lt/mokslas/moksliniai_tyrimai  
Loreta Alechnaviciute Hoffmann
Lithuania
Local time: 15:02
Native speaker of: Native in LithuanianLithuanian
PRO pts in category: 39
Notes to answerer
Ausri (X) Sutinku su Jūsų nuomone - terminas "biologinis įsisavinimas" atspindi minties esmę.


Votes in favor of/against selecting this as the best translation of the term asked
Yes  Ausri (X)
15 days
Yes  Saulene Kudarauskaite
90 days
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