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  3. Biology (-tech,-chem,micro-)

gene silencing

Croatian translation: "stišavanje" gena

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
English term or phrase:gene silencing
Croatian translation:"stišavanje" gena

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13:57 Feb 9, 2010
English to Croatian translations [PRO]
Science - Biology (-tech,-chem,micro-)
Additional field(s): Medical (general), Genetics
English term or phrase: gene silencing
Definition from MedicineNet, Inc.:
Gene silencing: A mechanism by which cells shut down large sections of chromosomal DNA. Gene silencing is done by incorporating the DNA to be silenced into a form of DNA called heterochromatin that is already silent. The process of gene silencing is important for the differentiation of many different types of cells.

Example sentence(s):
  • Evidence is emerging that geminiviruses and plant pararetroviruses can interact with the gene silencing system either from introduced DNA constructs or during viral pathogenesis. Some observations suggest there are complex relationships between DNA viral activity, transcriptional and post-transcriptional gene silencing mechanisms. biotech-info.net
  • The biggest challenges in the field at the moment are understanding two things: how does DNA methylation participate in gene silencing (and that includes what molecules target the DNA methylation to these promoter regions), and why is the cancer cell doing this? The Thomson Corporation
  • In 2005, Pikaard and his collaborators published research showing that the major function of Pol IV is to generate siRNAs, thereby singling out this RNA polymerase as a potential player in gene silencing. ScienceDaily LLC
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"stišavanje" gena
Definition:
Razvitak tehnika poput
interferencije RNK koja omoguæava
stišavanje gena koji
potièu bolesti i starenje, pokazala
je da se medicina transformirala
u informacijsku
tehnologiju, istièe šezdesetogodišnji
Kurzweil.
Selected response from:

PeregrineFalcon
Croatia
Grading comment
4 KudoZ points were awarded for this answer



Summary of translations provided
5 +2"stišavanje" gena
PeregrineFalcon
5utišavanje gena
Dinap


  

Translations offered


15 mins   confidence: Answerer confidence 5/5 peer agreement (net): +2
"stišavanje" gena


Definition from Vjesnik:
Razvitak tehnika poput
interferencije RNK koja omoguæava
stišavanje gena koji
potièu bolesti i starenje, pokazala
je da se medicina transformirala
u informacijsku
tehnologiju, istièe šezdesetogodišnji
Kurzweil.

Example sentence(s):
  • Craig Mello Izvor: Wikipedija Craig Cameron Mello (rođen 18. listopada 1960.) je američki biolog koji je 2006.g. dobio Nobelovu nagradu za fiziologiju ili medicinu zajedno sa Andrew Fireom za njihovo otkriće RNK interferencije (engl. RNA interference - RNAi) - stišavanja gena (engl. gene silencing) dvostrukom RNK. - Wikipedija  
  • Ključne reči: mijelodisplastični sindrom, hipermetilacija DNA, stišavanje gena, inhibitori DNA metiltransferaze Key words: Myelodysplastic syndrome. DNA hypermethylation, Gene silencing - Medicina danas  
  • Tim postupcima se neznatno mijenja genom (ukupna količina gena) ili se postojeći gen "pojačava" ili "stišava" da bi se dobilo željeno svojstvo unutar vrste. - Coolinarika  
PeregrineFalcon
Croatia
Local time: 10:42
Native speaker of: Native in CroatianCroatian
PRO pts in category: 4

Votes in favor of/against selecting this as the best translation of the term asked
Yes  Marija Horvat
6 days
  -> hvala:)
Yes  translana
8 days
  -> hvala:)
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18 mins   confidence: Answerer confidence 5/5
utišavanje gena


Definition from own experience or research:
To je metoda inaktivacije određenih gena kem. modifikacijama u svrhu izmjene njihove ekspresije u eukariota

Example sentence(s):
  • Utišavanje nekih gena u tumorima povezano je s pojačanom metilacijom u CpG otocima u regulatornim dijelovima tih gena. S obzirom da se u promotoru i prvom eksonu gena za Cx26 nalazi velik broj CpG dinukleotida, ispitivali smo povezanost ekspresije Cx26 i metilacije te regije gena. - Znanstveni rad_Hrv. znan.bibliografija  
  • Rezultati opisani u našem radu jasno pokazuju korisnost RNA interferencije kao metode za utišavanje gena u istraživanju raka, te pridonose razvoju in vitro modela za buduću gensku terapiju tumora. - znanstveni rad_hrv.znan. bibliografija  
Dinap
Croatia
Local time: 10:42
Native speaker of: Native in CroatianCroatian
PRO pts in category: 12
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in this pair and field What is ProZ.com Project History(SM)?
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