Cytoxicity was observed at 2.5 log10.

Chinese translation: 在2.5对数级观察到细胞毒性

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
English term or phrase:Cytoxicity was observed at 2.5 log10
Chinese translation:在2.5对数级观察到细胞毒性
Entered by: Jianming Sun

14:23 Feb 5, 2004
English to Chinese translations [PRO]
Medical - Biology (-tech,-chem,micro-) / virus
English term or phrase: Cytoxicity was observed at 2.5 log10.
Hi the toughest question:
In the result of an inactivation test of viruses with some culture cells inoculated with viruses, the sentence is “Results from hydrogen peroxide gas plasma sterilization half cycles challenged with hiv-1 are shown in Table 1. The titer of the virus control was 6.5 log10 for the first cycle and 6.25 log10 for the second half cycle. Cytoxicity was observed at 2.5 log10. Infectivity was not detected in the test samples at any dilution in any of the four replicates tested from the two cycles (2.5 log 10 for both cycles). Taking the toxicity results into consideration, the reduction in the HIV-1 titer was ≥3.75 log10 in the first sterilization cycle and ≥4.0 log10 in the second.” Question No.1: Does "Cytoxicity was observed at 2.5log10" mean there are about 102.5 viruses causing cytoxicity? Question No. 2: what does the “(2.5 log 10 for both cycles).”? Question No.3: How did they calculated the 3.75 and 4.0 log reductions ? Thanks!
Jianming Sun
Local time: 05:58
所观察到的细胞毒性为2.5 log10
Explanation:
Cytoxicity = 细胞毒性

在科学实验中处理数据时经常取其对数后绘图(换言之,使用对数坐标),使图形比例可以大为缩小;另一方面,对数运算有许多方便之处。log代表以10为底的对数。因log 10 = 1, 故log (10的n次方) =n log 10 = n。从这点出发试答上述问题如下:

Question No.1: Does "Cytoxicity was observed at 2.5log10" mean there are about 10 2.5 viruses causing cytoxicity?
No. It means about 10的2.5次方 viruses were killed?

Question No. 2: what does the “(2.5 log 10 for both cycles)” mean?
It just emphasizes “Cytoxicity was observed at 2.5 log10 for both cycles”.

Question No.3: How did they calculate the 3.75 and 4.0 log reductions?
6.25 log10 - 2.5 log10 = 3.75 log10
6.5 log10 - 2.5 log10 = 4.0 log10

以上谨供参考,希望能以此抛砖引玉。



--------------------------------------------------
Note added at 2004-02-05 20:05:49 (GMT)
--------------------------------------------------

After reading the text again, I think I should make a correction to the answer for Question No.1 as follows:
\"Cytoxicity was observed at 2.5 log10\" means \"Cytoxicity was observed at the titer of 2.5 log10\", i.e., 当滴定量为2.5 log10时观察到细胞毒性。


--------------------------------------------------
Note added at 2004-02-06 02:34:59 (GMT)
--------------------------------------------------

log A - log B = log (A/B)
So, (10的6.5次方)除以(10的2.5次方)equals 10的4次方

--------------------------------------------------
Note added at 2004-02-06 06:03:51 (GMT)
--------------------------------------------------

我所用的公式log A - log B = log (A/B)是对的。6.5 log10 - 2.5 log10 = log(10的6.5次方) - log(10的2.5次方) = log [(10的6.5次方)/(10的2.5次方)] = log (10的4.0次方) = 4.0 log10 。另一方面,因 log 10 =1,故6.5 log10 - 2.5 log10 = 6.5 - 2.5 = 4.0 = 4.0 log 10。

infectivity 和cytotocity确实是两回事。Infectivity是传染性。至于其它问题,我再查一查,你也可以问一下这方面的专家或你的用户。实在没有办法时就把语法关系搞清楚按照字面翻译,应该不会错。有些很专业的论文你要想完全从专业角度搞清楚恐怕很难。当然你的精神很好。



--------------------------------------------------
Note added at 2004-02-06 15:12:28 (GMT) Post-grading
--------------------------------------------------

FYI: 所谓4.0 log reduction 的概念是病毒数量下降到原来的1/10,000(即10的4次方之一)。
Selected response from:

ysun
United States
Local time: 16:58
Grading comment
Thank you! Yueyin. I had better close it and forget it.
3 KudoZ points were awarded for this answer



Summary of answers provided
4 +2所观察到的细胞毒性为2.5 log10
ysun
3 +1细胞毒性 为 2.5 log 10
Denyce Seow


Discussion entries: 7





  

Answers


1 hr   confidence: Answerer confidence 3/5Answerer confidence 3/5 peer agreement (net): +1
cytoxicity was observed at 2.5 log10.
细胞毒性 为 2.5 log 10


Explanation:
Is it "cytoxicity" or "cytotoxicity"??? I tried to find if there is any difference but I didn't get any good result. If they are the same, then here's my answer:

CYTOTOXICITY: Quality of being capable of producing a specific toxic action upon cells of special organs.

Cytotoxicity = 细胞毒性
简明英汉汉英医学词典


Denyce Seow
Singapore
Local time: 05:58
Native speaker of: Native in EnglishEnglish

Peer comments on this answer (and responses from the answerer)
agree  chica nueva: My first thought too...AmE?
8 hrs
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3 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +2
所观察到的细胞毒性为2.5 log10


Explanation:
Cytoxicity = 细胞毒性

在科学实验中处理数据时经常取其对数后绘图(换言之,使用对数坐标),使图形比例可以大为缩小;另一方面,对数运算有许多方便之处。log代表以10为底的对数。因log 10 = 1, 故log (10的n次方) =n log 10 = n。从这点出发试答上述问题如下:

Question No.1: Does "Cytoxicity was observed at 2.5log10" mean there are about 10 2.5 viruses causing cytoxicity?
No. It means about 10的2.5次方 viruses were killed?

Question No. 2: what does the “(2.5 log 10 for both cycles)” mean?
It just emphasizes “Cytoxicity was observed at 2.5 log10 for both cycles”.

Question No.3: How did they calculate the 3.75 and 4.0 log reductions?
6.25 log10 - 2.5 log10 = 3.75 log10
6.5 log10 - 2.5 log10 = 4.0 log10

以上谨供参考,希望能以此抛砖引玉。



--------------------------------------------------
Note added at 2004-02-05 20:05:49 (GMT)
--------------------------------------------------

After reading the text again, I think I should make a correction to the answer for Question No.1 as follows:
\"Cytoxicity was observed at 2.5 log10\" means \"Cytoxicity was observed at the titer of 2.5 log10\", i.e., 当滴定量为2.5 log10时观察到细胞毒性。


--------------------------------------------------
Note added at 2004-02-06 02:34:59 (GMT)
--------------------------------------------------

log A - log B = log (A/B)
So, (10的6.5次方)除以(10的2.5次方)equals 10的4次方

--------------------------------------------------
Note added at 2004-02-06 06:03:51 (GMT)
--------------------------------------------------

我所用的公式log A - log B = log (A/B)是对的。6.5 log10 - 2.5 log10 = log(10的6.5次方) - log(10的2.5次方) = log [(10的6.5次方)/(10的2.5次方)] = log (10的4.0次方) = 4.0 log10 。另一方面,因 log 10 =1,故6.5 log10 - 2.5 log10 = 6.5 - 2.5 = 4.0 = 4.0 log 10。

infectivity 和cytotocity确实是两回事。Infectivity是传染性。至于其它问题,我再查一查,你也可以问一下这方面的专家或你的用户。实在没有办法时就把语法关系搞清楚按照字面翻译,应该不会错。有些很专业的论文你要想完全从专业角度搞清楚恐怕很难。当然你的精神很好。



--------------------------------------------------
Note added at 2004-02-06 15:12:28 (GMT) Post-grading
--------------------------------------------------

FYI: 所谓4.0 log reduction 的概念是病毒数量下降到原来的1/10,000(即10的4次方之一)。

ysun
United States
Local time: 16:58
Native speaker of: Chinese
PRO pts in category: 39
Grading comment
Thank you! Yueyin. I had better close it and forget it.

Peer comments on this answer (and responses from the answerer)
agree  Denyce Seow: wow, I didn't notice the three questions!! You're a maths expert too!! FYI, I hate logarithms too. You must wonder how I pass my exams??? I was a GPA4.0 student though!! Haha.
7 mins
  -> Thanks! I can tell you are very smart, but may not be hard-working! : )

neutral  technotran: Note that the word cytoxicity maybe a wrong spelling. The usual spelling is cytotoxicity.
295 days
  -> Thank you!

agree  nina yang
2132 days
  -> Thank you!
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