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04:14 Oct 13, 2007 |
English to Chinese translations [PRO] Medical - Biology (-tech,-chem,micro-) / biotech | |||||||
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| Selected response from: Han Li China Local time: 15:07 | ||||||
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4 | 与活化的Fc-γ受体结合 |
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bound activating fc-gamma receptors 与活化的Fc-γ受体结合 Explanation: -------------------------------------------------- Note added at 32 mins (2007-10-13 04:47:18 GMT) -------------------------------------------------- Fcγ受体有3类:FcγRI (CD64,一种高亲和性受体)、 Fcγ RII和 RIII (又分别称为CD32 和CD16,都属于低亲和性受体)。 -------------------------------------------------- Note added at 39 mins (2007-10-13 04:54:24 GMT) -------------------------------------------------- Fc受体(Fc receptors,FcR)是结合免疫球蛋白(Ig)Fc段的表面分子,可识别抗体决定簇。 -------------------------------------------------- Note added at 4 hrs (2007-10-13 08:21:01 GMT) -------------------------------------------------- 你的理解是正确的,我又查了一点资料: Fc受体γ链是Fc受体(包括FcαR、FcεR、FcγRⅠ、FcγRⅡA、FcγRⅢA)的一个组成亚单位,γ链以同源二聚体的形式组成Fc受体的跨膜段和胞内段。Fc受体γ链的存在增强Fc受体与免疫球蛋白的亲和力。在免疫应答过程中,Fc受体与免疫复合物结合后,通过γ链中的免疫受体酪氨酸的活化基因序列向细胞内传递活化信号。 http://www.labweb.cn/articleview/2006-10-14/article_view_359... 因此应该是具有活化作用的Fc-γ受体 -------------------------------------------------- Note added at 4 hrs (2007-10-13 08:23:10 GMT) -------------------------------------------------- activating有“活化”和“具有活化作用”两层意思,但具体是哪一个解释应该从受体的结构和作用来看,这就需要查相关的资料了。 |
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